STUDIES OF REACTIVITY OF AMINO GROUP IN THE 2-, 6-, 7- POSITION OF 1,4-NAPHTHOQUINONE

2018;
: 88-97
1
Lviv Polytechnic National University
2
Lviv Polytechnic National University
3
Lviv Polytechnic National University
4
Lviv Polytechnic National University
5
Lviv Polytechnic National University

The nucieophilic properties of amino group in the 2-position of the 1,4-naphthoquinone
in the reactions of alkylation, acylation, and also in interaction with sulfinyl chlorides and
sulfonyl chlorides in comparison with the nucieophilic properties of the amino groups in the 6-
and 7-position has been investigated. It was found that in the presence of an amino group in
the molecule of substituted 1,4-naphthoquinone there is a displacement of the electron density
in the direction of the 1,4-naphthoquinone ring with an appropriate charge change on the
carbon atoms in a certain position, thus the reactivity of the amino group in the alkylation
reaction is highest at the 7-th carbon atom, some the lower activity of the amino group in the 6-
th position and the lowest in the 2-position of the 1,4-naphthoquinone

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