лікарський засіб пролонгованої дії

Розробка інкапсульованого лікарського засобу на основі налтрексону та дисульфіраму

The paper considers the possibility of creating a combined injection drug prolonged action based on naltrexone and disulfiram by encapsulation method. Polymers of poly-D, L-lactide-co-glycolide lactic acid were selected as adjuvant. Optimal method of process was developed based on the analysis of the literature, patent research and experimental data. Spheres of micro-and nano- sizes based on naltrexone and disulfiram as a powder for use as an injection were obtained.