Composite hydrogel metal-filled materials in many cases during the operation are used in the form of films, in medicine these are membrane different kind, of transdermal drugs, implants, elements of medical equipment intended for installation of a reliable contact with the human body, the instrument making-elements of different sensors (humidity, temperature, pressure, concentration of gaseous and liquid products), etc.

Film hydrogels on the basis of polyvinylpyrrolidone copolymers with regulated sorption-desorption characteristics

The hydrogel film composites of biomedical purpose based on copolymers of polyvinylpyrrolidone with 2-hydroxyethylmethacrylate have been synthesized. The influence of filler nature, quantity and composition on the regularities of obtaining, structure and properties of hydrogels have been determined. Synthesized hydrogel composites are recommended to be used for the controlled drug release systems.

The peculiarities of the polyvinylpyrrolidone copolymers synthesis for contact lenses

The research results of the hydrogels synthesis rules on the basis of 2-hydroxyethylmethacrylate-polyvinylpyrrolidone copolymers and effective ways of adjusting of their proper¬ties are given. Synthesized copolymers appeared to be effective materials for production of hydrophilic contact lenses.

Hydrogels Penetration and Sorption Properties in the Substances Release Controlled Processes

The crosslinked copolymers of 2-hydroxyethylmethacrylate with polyvinylpyrrolidone as granules and membranes have been synthesized and their penetration and sorption-desorption properties have been investigated. The model of mass-transfer from the solid soluble surface through the hydrogel shell has been suggested. The developed materials are able to create encapsulated and granular polymer forms of drugs prolonged release.

Matrix Polymerization of 2-Hydroxyethylmethacrylate in the Presence of Polyvinylpyrrolidone in Permanent Magnetic Field

The influence of a constant magnetic field on the polymerization kinetics and structural parameters of a hydrogel network on the basis of 2-hydroxyethylmethacrylate and polyvinylpyrrolidone compositions has been investigated. It has been shown that the magnetic field activates matrix polymerization of such compositions and assists in structure formation of copolymers with minor cross-link density. The efficiency of the developed polymeric materials used for production of ultrathin contact lenses has been confirmed.

Optimization of 2,3-Dimethylbuta-1,3-diene and 2-Hydroxyethylmethacrylate Cyclization Reaction Conditions

Based on the experimental studies and mathematical modeling method, we have chosen the optimal conditions of the 2,3-dimetylbuta-1,3-diene and 2-hydroxyethylmethacrylate cyclization reaction with obtaining of 2-hydroxyethyl 1,3,4-trimethylcyclohex-3-encarboxylate.

Structure Controlled Formation and Properties of Highly Hydrophilic Membranes Based on Polyvinylpyrrolidone Copolymers

Polymerization of hydroxyalkyl(meth)acrylates with polyvinylpyrrolidone has been investigated. Thus highly hydrophilic membranes have been obtained and several properties have been investigated including polymerization rate, viscosity, extinction, water permeability of the membranes, their tensile strength and tensile elongation at break. Parameters characterizing complex formation between monomer and polyvinylpyrrolidone are related to structural parameters of resulting copolymer networks.

The Role of FeSO4 in the Obtaining of Polyvinylpirrolidone Copolymers

The proceeding of 2-hydroxyethylmethacrylate grafted polymerization on polyvinylpirrolidone has been examined in the presence of ferrum(II) sulfate. It was observed the formation of crosslinked copolymer capable to be used as a matrix for metal chemical reduction and for metal hydrogel composites obtaining. The effect of Fen+ structure and concentration on the structural parameters of the polymeric network, copolymers composition, efficiency and degree of grafting has been determined.

Effect of the Reactants Molar Ratio on the Kinetics of the Reaction to Obtain 2-hydroxyethyl-1,3,4 trimethyl-cyclohex-3-encarboxylate

Kinetic aspects of the reaction of 2-hydroxyethyl-1,3,4-trimethylcyclohex-3-ene-1-carboxylate obtaining have been investigated. On the basis of the obtained results the kinetics of the process has been studied by the Michaelis-Menten equation. The limiting stage of the reaction is established and its mechanism is suggested.

Mineral Filled Porous Composites Based on Polyvinylpyrrolidone Copolymers with Bactericidal Properties

The polymerization of 2-hydroxyethylmethacrylate compositions with polyvinylpyrrolidone has been investigated in the presence of mineral fillers (hydroxyapatite, montmorillonite and wollastonite). The influence of the nature and amount of mineral filler on polymerization kinetics and composition of copolymers has been determined. In the composite structure silver particles were obtained via silver nitrate reduction by polyvinylpyrrolidone tertiary nitrogen. The synthesized silver-containing composites possess bactericidal properties against E. colі and S. aureus bacteria, in particular.