THERMODYNAMIC PROPERTIES OF THE SOLUBILITY OF ESTERS OF 6-METHYL-2-OXO-4-ARYL-1,2,3,4-TETRAHIDROPIRYMIDYN-5- CARBOXYLIC ACID IN ACETONITRILE
The derivatives of 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid are the simplest representatives of Bidzhenelli’s dyhidropirymidynes and are characterized by a wide range of biological activity. It is important to use pure substances at each stage of the synthesis in the pharmaceutical industry. The main method of solid substances purifying is recrystallization using the so-called "classic" solvents, which include acetonitrile.