DNA

The binding free energy of 9N-(ferrocenylmethyl)adenine (FMA) with double-stranded deoxyribonucleic acid (DNA) was measured in solution using cyclic voltammetry and electronic spectroscopy (UV-Vis) techniques under similar conditions. The obtained results were confirmed by computational molecular docking. The docking studies yield good approximation with experimental data and showed that the ligand FMA is placed in the minor groove of DNA.

 In this paper properties of deoxyribonucleic acid (DNA) complexes with originally proposed cationic surfactants are described. Properties of prepared complexes were studied with the help of UV-vis-NIR and FT-IR spectroscopies, TGA and DSC analysis and X-ray diffractometry. These complexes are intended for future applications in organic electronics.