Al2(SO4)3·18H2O as an Eco-Safe Catalyst Promoting Synthesis of Polysubstituted Dihydropyrrol-2-ones
Aluminum sulfate octadecahydrate (Al2(SO4)3•18H2O) as an efficient, mild and eco-safe catalyst for one-pot four-component synthesis of polysubstituted dihydropyrrol-2-ones from reaction between dialkyl acetylenedicarboxylate, formaldehyde and amines (aromatic and aliphatic) under ambient temperature with good to high yields and short reaction times is reported.