THERMODYNAMIC PROPERTIES OF METHYL ESTER OF 6-METHYL-2-OXO-4-ARYL-1,2,3,4- TETRAHIDROPIRYMIDYN-5-CARBOXYLATE IN ETHYLACETATE AND BENZENE AND THEIR MIXTURE
The purpose of this work is to investigate the thermodynamic properties of the solubility of methyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylate, which exhibits a wide spectrum of biological activity in organic solvents of different polarity and their character of mixing. As you know, the processes of synthesis and purification of solid substances, allmost, occur with the help of individual solvents or their mixture, so optimization of these processes is impossible without determining the thermodynamic parameters of their dissolution.