N-метилпіперазин

The Synthesis and Antimicrobial Properties of New 2-(R-Phenylimino)-1,3-thiazoline Derivatives Containing the N-Methylpiperazine Moiety

New derivatives of N-(R-phenyl)-3-(4-methyl-1-piperazinyl)-1,3-thiazole-2(3H)- imine with the medium to high yields were synthesized by the Hantzsch reaction in the ethanol medium. The structure of target compounds was confirmed by elemental analysis and NMR spectroscopy. The antimicrobial activity of 1,3-thiazoline derivatives with the N-methylpiperazine moiety against sulfate-reducing bacteria of Desulfovibrio sp. М.4.1 strain was studied.