Optimization Studies on Biosynthesis of Citric Acid by One-Factor-at-a-Time
In the presented study, the significant operating variables regarding biosynthesis of citric acid process were assessed and their effects on the process yield were analysed. These variables, namely, initial sucrose concentration, methanol concentration, inoculum density, initial medium pH, spore age, stirrer speed, incubation period, fermentation temperature, particle size distribution, oxygen flow rate, and moisture content have significant influence on bioprocess of citric acid production.