MODIFICATION OF BENZYLPHTHALIMIDE BY THIOSULFONATE FRAGMENT AND VIRTUAL SCREENING OF BIOLOGICAL ACTIVITY OF OBTAINED TIOSOLPHOESTERS
Cyclic imides are privileged pharmacophores and important building blocks for the synthesis drugs, agrochemicals, advanced materials and polymers. A number of valuable natural products contain an imid fragment in their structure, in particular, Migrastatin, lamprolobin, julocrotine, cladoniamide A.