calcium silicophosphate glass-ceramic materials

Availability of chitosan for obtaining of biocide apatite glass-ceramic materials for bone endoprosthetics has been confirmed. Comparative assessment of biocide properties against Саndida albican, and Escherichia coli of materials used for bone endoprosthetics has been made. The use of implants on the base of calcium silicophosphate glass-ceramic materials saturated with chitosan will allow to decrease the possibility of inflammatory processes caused by infection and to shorten the terms of resorption of biomaterial with a bone.

Nanostructural changes on initial stages of calcium silicophosphate glasses nucleation in Na2О–CаO–ZnO–TiO2–ZrO2–Al2O3–B2O3–P2O5–SiO2 system during phase separation have been investigated. It has been established that the presence of drop-shaped nano- and micro-nonuniformities in the structure of calcium silicophosphate glasses substantially affects the glass separation in a precrystallization period, helping intense fine hydroxyapatite crystallization with the crystal size of up to 1 μm after heat treatment.