Dextran-graft-Polyacrylamide copolymers (D-g-PAA) with a polysaccharide backbone having different molecular weights (Mw = 20 000 and Mw = 70 000) and with various number of PAA-grafts per one Dextran macromolecule have been synthesized. Light scattering and viscometry investigations have shown that the internal structure of D-g-PAA copolymers depends upon the distance between PAA-grafts.
Dextran methacrylates were received by acylation of dextran with methacryloilchloride in the presence of tertiary amines in the DMF/LiCl solution. Degree of substitution (DS) of synthesized derivatives reached 1.8 methacrylic residues per glucopyranoside unit of dextran macromolecule. Dextran methacrylates, obtained in the presence of triethylamine, with DS over 0.5 were insoluble in water. Derivatives synthesized in the presence of pyridine were separated in the form of a stable water soluble complex with pyridine chloride. These complexes maintain their water solubility up to DS = 1.8.