2-гідроксиетилметакрилат

Ефект параметра розчинності у суспензійній полімеризації композицій метакрилових естерів з полівінілпіролідоном

The effect of the solubility parameter on the regularities of the hydrogel suspension obtaining based on the copolymers of 2-hydroxyethyl methacrylate and glіcidil metakrilat with polyvinylpirrolydone is investigated. The influence of the solvent nature on the diffusion processes in the suspension polymerization, the dispersion characteristics of hydrogel particles and kinetics of polymerization is determined.

Possibility of Using Embolizing Preparation Derived from Poly(2-Hydroxyethyl Methacrylate) (Poly-HEMA) for Chemoemobolization

The principal opportunity of uptaking weakly crosslinked hydrogel emboli is shown by Doxorubicin at different temperatures. The optimal process time is 1.5–2.5 h. It is revealed that Doxorubicin is capable to diffuse from a polymeric matrix, having targeted medical effect on surrounding tissue and reducing side impacts on other organs.