Investigation of hydrolytic degradation of polyhydroxyalkanoates and their mixtures with polylactides

The hydrolytic degradation of polyhydroxyalkanoates, polylactide and their mixtures in vitro in physiological solution and phosphate-salt buffer as well was researched. The hydrolysis intensity of biopolymers was evaluated via the mass loss, change in molecular weight as well as the water absorption applying the methods of infrared spectroscopy and complex thermal analysis. It was determined that films based on the researched biodegradable polymers thermostated in a phosphate-salt buffer have been degrading faster than in physiological solution.

 

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