In this work agar- and borax-based hydrogels with and without the addition of poly(vinyl alcohol) (PVA) at different concentrations were synthesized. Hydrogels were modified by the same amount of acetylsalicylic acid (ASA) which exhibits antithrombotic properties. The effect of modification by ASA on the properties of hydrogels was analyzed.
Acetylsalicylic acid, paracetamol, and ascorbic acid which are used for the pain reliever and fever reducer were analyzed without any prior reservation by means of spectrophotometry-chemometry. The experimental calibration matrix was designed by measuring the absorbance within the range of 200–400 nm for 19 samples of acetylsalicylic acid, paracetamol, and ascorbic acid. Absorbance and concentration values were analyzed using Minitab and other chemometric programs to calculate estimated concentrations by PCR and PLSR.