Study of calcium profile in neuronal cells with respect to temperature and influx due to potential activity
Calcium is a critically important second messenger in the nervous system. It enters through voltage-gated Ca2+ channels and regulates the release of the synaptic transmitter. This mechanism is monitored by calcium diffusion, buffering mechanism and calcium influx into the cytoplasm. The study of Ca2+ dynamics is interesting because the concentration of Ca2+ shows highly complex spatial-temporal behavior. There are many controls on the cytoplasmic Ca2+ concentration. First, it is heavily buffered (i.e., bound) by large pro