Schiff base

Synthesis, Biological and Acidic Properties of Novel 2-Methoxy-6-[(3-Alkyl/Aryl-4,5-Dihydro-1H- 1,2,4-Triazol-5-one-4-yl)-Azomethin]-Phenyl p-Nitrobenzoate Derivatives

3-Alkyl/Aryl-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) reacted with 2-(p-nitrobenzoxy)-3-methoxybenzaldehyde (3) to afford the corresponding 2-methoxy-6-[(3-alkyl/aryl-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl)-azomethin]-phenyl p-nitrobenzoates (4). The acetylation reactions of compounds 4 were investigated, and 5 type N-acetyl derivatives were obtained. The newly synthesized compounds were fully characterized. Also, in vitro antibacterial activities of the fourteen new compounds were screened against six bacteria according to agar well diffusion method.

Synthesis, Characterization and Biological Activity of Mixed Ligand (Imine of Benzidine and 1,10-Phenanthroline) Complexes with Fe(II), Co(II), Ni(II) and Cu(II) Ions

In this paper, binuclear metal complexes of the metal ions Fe(II), Co(II), Ni(II) and Cu(II) were synthesized by the reaction of the primary ligand (imine of benzidine) (H2L) and the secondary ligand (1,10-phenanthroline) (L`) with these metal ions in a molar ratio of 1:2:2, respectively. The complexes were characterized using CHN elemental analysis, FT-IR, UV-Vis, magnetic susceptibility, molar conductivity, 1H NMR, and TGA-DTA thermogravimetric analysis.

Solid Melamine Sulfate for Schiff Base Synthesis

Melamine sulfate (Si-MelaSO4H) was prepared by treated melamine, which was immobilized onto silica (Si-Mela) with 0.05 M sulfuric acid at room temperature. The TGA confirmed that the thermal stability could reach 473 K. The XRD pattern showed that in some patterns there were sharp peaks and in other pattern a broad band was shown, which indicated that the surface is a mix of crystalline and non-crystalline nature. The Si-MelaSO4H was used successfully in the preparation of Schiff bases and its derivatives.