antioxidant

Algerian flora contains a wide range of aromatic plants of great therapeutic interest thanks to their biologically active secondary metabolites which makes them a subject of scientific interest. In this work, we were interested in Ocimum basilicum L. of Lamiaceae family cultivated and harvested in Biskra city located at South-East of Algeria. Phytochemical screening has been per-formed to reveal the presence of flavonoids, tannins, coumarins, essential oil, and other phytochemicals. The contents of total polyphenols, total flavonoids and total tannins have been determined.

Snails are often found in Indonesia, especially at Kediri, but the snail shell has no commercial value. This research report describes the characterization and antioxidant activity of chitosan from snail shell waste (chitosan-SSW) by ultrasonic technique and analyzes the potential of chitosan as an inhibitor of receptors of free radicals using an in silico molecular docking method.

Some new hydroxyxanthone compounds were prepared through one pot cyclodehydration reaction of hydroxybenzoic acid derivatives (salicylic acid or resorcylic acid) with phloroglucinol or pyrogallol in the presence of Eaton’s reagent (P2O5/MeSO3H). The synthesized compounds were screened for their antioxidant activities by 2,2-diphenyl-1-picrylhydrazyl (DPPH) methods to determine their inhibitory concentration (IC50). Cytotoxicity of the prepared compounds was also evaluated by MMT assay on Vero cell line.

The total amount of antioxidants and their activity with respect to oxygen and its radicals are measured in water extract of mint peppery (Mentha piperita L.) by two electrochemical methods: ammetric and voltammetric. Mechanisms of interaction of antioxidants with oxygen and its radicals have been investigated

Energies of formation, enthalpies, and entropies of the conformers of 1-(carboxy)-1-(N-methylamide)-2-(3',5'-di-tert-butyl)-4-hydroxyphenyl)-propionic acid and sodium and potassium 1-(carboxy)-1-(N-methylamide)-2-(3',5'-di-tert-butyl)-4-hydroxyphenyl)-propionates are calculated by quantum-chemical methods in the PM6 approximation. A doubling of signals in the 1H NMR spectrum of the first conformer is observed, which merge into singlets when the compound is heated.

Toxicity of 28 phenol derivatives with different alkyl substitutes in 2-, 6-positions and NH2 , CN, ОН functional groups in 4-position was studied. The least toxicity has phenols with two tert-butyl substitutes in o-position. The toxicity increases with functional p-substitutes removal from benzene nuclei. The obtained results can help to synthesize new nontoxic bioactive phenols.