drug delivery system

This study focuses on creating a method to produce ion-crosslinked alginate-based hydrogel systems that enable immediate drug release. The research investigates the kinetics of releasing a bactericidal drug to facilitate the healing process relief. The technique involves enhancing the immobilization of amphiphilic medicines on calcite microparticles, followed by concentrating them in the pores formed through a microparticle decomposition.

The paper describes synthesis and colloidal properties of novel α-amino acid based polyesters with controllable hydrophilic-lipophillic balance. Polyesters based on glutamic acid and glycols of different nature were obtained via low-temperature activated polyesterification. Such polymers are able to form micellar structures in self-stabilized water dispersion. Peculiarities of Steglich rection in the case of polyesterefication and side processes were established and optimal conditions for polyester synthesis were determined.