Synthesis and properties of 4,6-dimethylpyrimidine-2-yl esters of aromatic thiosulfoacids.

2020;
: 117-124
1
Lviv Polytechnic National University
2
Lviv Polytechnic National University
3
Lviv Polytechnic National University
4
Lviv Polytechnic National University
5
Lviv Polytechnic National University
6
Lviv Polytechnic National University

Methods for the synthesis of thiosulfoesters with a pyrimidine moiety were investigated by the interaction of sulfinic acids with 4,6-dimethylpyrimidine-2-yl sulfenamide. The interaction of 4,6-dimethylpyrimidin-2-yl esters of aromatic thiosulfoacids with amines (benzylamine, morpholine, ammonia) was investigated. It is established that the interaction of synthesized 4,6-dimethylpyrimidin-2-yl thiosulfoacid esters with different amines is interesting not only in terms of studying the properties of thiosulfoesters, but also as an interaction with significant practical value, since it can be proposed for use as a new method of synthesis pyrimidine sulfenamides. The structure and individuality of the synthesized compounds were confirmed by IR, 1H NMR spectroscopy, elemental analysis and TLC method.

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