Developing Materials for Biodegradable Otolaryngological Stents

2023;
: pp. 24 - 34
1
Department of Polymer Technology, Faculty of Chemistry, Gdansk University of Technology
2
Department of Polymer Technology, Faculty of Chemistry, Gdansk University of Technology
3
Department of Polymer Technology, Faculty of Chemistry, Gdansk University of Technology
4
Department of Polymer Technology, Faculty of Chemistry, Gdansk University of Technology
5
Gdansk University of Technology
6
Department of Polymer Technology, Faculty of Chemistry, Gdansk University of Technology

Materials for otolaryngological stents have to be characterized by good tensile strength, wear resistance, biocompatibility, and specific degradation time. This work aimed to synthesize polyurethanes based on various biodegradable polyol blends. Their biodegradability and mechanical properties were tested and compared to commercial BIOFLEX material.

  1. Vert, M.; Doi, Y.; Hellwich, K.-H.; Hess, M.; Hodge, P.; Kubisa, P.; Rinaudo, M.; Schué, F. Terminology for Biorelated Polymers and Applications (IUPAC Recommendations 2012). Pure Appl. Chem. 2012, 84, 377-410. https://doi.org/10.1351/PAC-REC-10-12-04
  2. Velasco, M.A.; Narváez-Tovar, C.A.; Garzón-Alvarado, D.A. Design, Materials, and Mechanobiology of Biodegradable Scaffolds for Bone Tissue Engineering. Biomed Res. Int. 2015, 2015, 729076. https://doi.org/10.1155/2015/729076
  3. Hung, K.-C.; Tseng, C.-S.; Hsu, S.-H. 3D Printing of Polyurethane Biomaterials. In Advances in Polyurethane Biomaterials; Elsevier, 2016; pp 149-170. https://doi.org/10.1016/B978-0-08-100614-6.00005-6
  4. Zubyk, H.; Mykhailiv, O.; Papathanassiou, A.N.; Sulikowski, B.; Zambrzycka-Szelewa, E.; Bratychak, M.; Plonska-Brzezinska, M.E. A Phenol-Formaldehyde Polymeric Network to Generate Organic Aerogels: Synthesis, Physicochemical Characteristics and Potential Applications. J. Mater. Chem. A 2018, 6, 845-852. https://doi.org/10.1039/C7TA08814K
  5. Bratychak, M.; Bratychak, M.; Brostow, W.; Shyshchak, O. Synthesis and Properties of Peroxy Derivatives of Epoxy Resins Based on Bisphenol A: Effects of the Presence of Boron Trifluoride Ethereate. Mater. Res. Innov. 2002, 6, 24-30. https://doi.org/10.1007/s10019-002-0157-7