Study of calcium profile in neuronal cells with respect to temperature and influx due to potential activity

Calcium is a critically important second messenger in the nervous system.  It enters through voltage-gated Ca2+ channels and regulates the release of the synaptic transmitter.  This mechanism is monitored by calcium diffusion, buffering mechanism and calcium influx into the cytoplasm.  The study of Ca2+ dynamics is interesting because the concentration of Ca2+ shows highly complex spatial-temporal behavior.  There are many controls on the cytoplasmic Ca2+ concentration.  First, it is heavily buffered (i.e., bound) by large proteins and second control is that of the variable diffusion coeffi

Mathematical modeling of temperature variation in breast tissue with and without tumor/cyst during menstrual cycle

The thermoregulation of human female body is influenced by hormonal and physiological changes in the body during the menstrual cycle.  The fluctuation of estrogen and progesterone hormones, release in the follicular phase and the luteal phase of menstrual cycle, respectively play an important role in the growth of breast ducts and lobules (milk glands).  The imbalance of these hormones causes breast tumors/cysts.  The body core temperature, blood perfusion and metabolism rate are higher in the luteal phase than the follicular phase of menstrual cycle.  In the present work, a tumor/cyst is a

Optimization of the structures by the static strength and the frequency characteristics

Problems of determination of optimal geometric and constructive parameters of long-length structures are presented. For example, a longitudinal profile of a complicated section is adopted, its components of the stress state and its own oscillation frequencies are determined. The choice of optimal profile parameters is made for the implementation of structures with minimum equivalent stresses, as well as for ensuring maximum dynamic stiffness.