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  3. Volume 10, Number 3, 2023
  4. Tikhonov regularization for a spatiotemporal model of the human monkeypox outbreak

Tikhonov regularization for a spatiotemporal model of the human monkeypox outbreak

MMC.
2023;
Volume 10, Number 3
: pp. 875–888
https://doi.org/10.23939/mmc2023.03.875
Received: November 26, 2022
Revised: April 17, 2023
Accepted: April 18, 2023

Mathematical Modeling and Computing, Vol. 10, No. 3, pp. 875–888 (2023)

Authors:
  1. K. Marouane
  2. S. Ben Rhila
  3. A. Kouidere
  4. M. Rachik
1
Laboratory of Analysis Modeling and Simulation, Department of Mathematics and Computer Science, Faculty of Sciences Ben M'sik, Hassan II University of Casablanca
2
Laboratory of Analysis, Modelling and Simulation, Department of Mathematics and Computer Science, Faculty of Sciences Ben M'sik, Hassan II University of Casablanca
3
Laboratory of Analysis Modeling and Simulation, Department of Mathematics and Computer Science, Faculty of Sciences Ben M'sik, Hassan II University of Casablanca
4
Laboratory of Analysis Modeling and Simulation, Department of Mathematics and Computer Science, Faculty of Sciences Ben M'sik, Hassan II University of Casablanca

Monkeypox is a contagious disease caused by the monkeypox virus.  There is currently an outbreak of monkeypox in the U.S. and other countries where the virus is not usually seen.  We develop and analyze a deterministic mathematical model for the monkeypox virus by proposing a spatiotemporal model describing the dynamics of the virus between humans.  The existence, the positivity, and the boundedness of the solutions have been proved.  Moreover, with the help of the optimal control, we add two different controls (blocking of contact and treatment in the case of infection) to prevent the propagation of monkeypox between humans. Finally, we present brief comments and numerical simulations to illustrate our findings.  The results show that keeping diseased people apart from the general population minimizes the spread of disease.

spatial-temporal transmission
Human Monkeypox
Tikhonov regularization
optimal control
numerical simulation
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