1. JCCT
  2. All Volumes and Issues
  3. Volume 13, Number 4, 2019
  4. Physico-Chemical Characterization of Bioactive Mixed Ligand Complexes of Antimony with 3,5-Diarylsubstituted Pyrazolinates and O,O’-Alkylene Dithiophosphates

Physico-Chemical Characterization of Bioactive Mixed Ligand Complexes of Antimony with 3,5-Diarylsubstituted Pyrazolinates and O,O’-Alkylene Dithiophosphates

JCCT.
2019;
Volume 13, Number 4
: pp. 407 - 416
https://doi.org/10.23939/chcht13.04.407
Authors:
  1. Kanchan Lata Singh
  2. Afshan Siddiqui
  3. Kajal Singh
  4. Umesh NathTripathi
1
Department of Chemistry, DDU Gorakhpur University
2
Deen Dayal Upadhyaya Gorakhpur University
3
Department of Chemistry, DDU Gorakhpur University
4
Deen Dayal Upadhyaya Gorakhpur University

Antimony(III) complexes of 3(2’-hydroxyphenyl)-5-(4’-substituted phenyl) pyrazolinates and O,O’-alkylene dithiophosphate of the type [Sb(C15H12N2OX)(GO2PS2)]Cl and [Sb(C15H12N2OX)2(GO2PS2)] (where GO2PS2 – deprotonated O,O’-alkylene dithiophosphate; C15H12N2OX – deprotonated 3(2'-hydroxyphenyl)-5-(4’-subsitutedphenyl) pyrazolinates; X = –H,–CH3, –OCH3 and –Cl; G = –C(CH3)2CH2CH(CH3)–) have been synthesized and characterized by elemental analysis (C, H, N, Cl and Sb), molecular weight study by FAB mass, electronic spectral studies, far and mid IR, multinuclear NMR (1H,13C and 31P). On the basis of above spectral studies, coordination of dithiophosphate and pyrazolinates along with the compounds structure have been discussed tentatively. All complexes were tested for in vitro antibacterial and antifungal activity, exhibiting a very good antibacterial and antifungal activity. Few complexes were also tested for their antiviral activity against papya ringspot virus showing a significant antiviral activity with inhibition of approximately 34.30 %.

antibactirial activity
antiviral activity
antimony(III)
pyrazolinates
dithiophosphates
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