sodium alginate

The production of silver nanoparticles was carried out in an aqueous medium treated by discharge of the contact non-equilibrium low-temperature plasma in the presence of sodium alginate (1.25–5.0 g/l). The formation of silver metal particles (to 100 nm) was confirmed by X-ray diffraction and IR spectroscopy analysis. The obtained colloidal solutions of silver nanoparticles lead to the formation of thinner biofilm under microbial corrosion of mild steel, initiated by sulfate reducing bacteria of Desulfomicrobium genus.

The various samples of pectins with degrees of esterification of 40-70% in the work were obtained using pectin with degree of esterification of 81.5%. It was shown that the determining factor for successful formation of hydrogel plates is the degree of esterification of polysaccharide. It was established that hydrogel plates obtained by the method of structuring of calcium salts are formed only on the basis of pectin with the degree of esterification less than 70%.

pH-Responsive microspheres were prepared and their feasibility as potential carriers for oral delivery of protein drugs was evaluated. The microspheres were prepared from the ionotropically-crosslinked mixture of sodium alginate and κ-carrageenan. The morphology and size of the microspheres were investigated. A model protein drug α-amylase was entrapped and in vitro drug release profiles were established. The preliminary investigation of the microspheres showed a consistent swelling pattern, high entrapment efficiency and sustained release profiles of the enzyme.