1. CTAS
  2. All Volumes and Issues
  3. Volume 7, Number 2
  4. HYDROGELS BASED ON NATURAL POLYMERS STRUCTURED WITH PROPYLENE GLYCOL DIEPOXIDE FOR DRUG DELIVERY

HYDROGELS BASED ON NATURAL POLYMERS STRUCTURED WITH PROPYLENE GLYCOL DIEPOXIDE FOR DRUG DELIVERY

CTAS.
2024;
Volume 7, Number 2
: 176-183
Authors:
  1. A. V. Hnyp
  2. Natalya Bukartyk
  3. О. V. Maikovych
  4. Yu.V. Cherkas
  5. Nataliia Nosovа
  6. Serhii Varvarenko
1
Lviv Polytechnic National University
2
Lviv Polytechnic National University
3
Lviv Polytechnic National University
4
Lviv Polytechnic National University
5
Lviv Polytechnic National University
6
Lviv Polytechnic National University

The article presents the conditions of synthesis and the results of characterization of the obtained gelatin and gelatin-alginate hydrogels structured with polypropylene glycol diepoxide. The swelling in water, saline, and model exudate was studied, and the gel fraction and tensile strength of the synthesized samples were determined. The regularities of saturation with drugs and their release into model environments were obtained. The potential use of these materials for transdermal drug delivery is considered.

structuring
gelatin
sodium alginate
swelling in model media
drug release
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