У цій роботі успішно синтезовано серію нових похідних 4,5-дигідро-1H-піразолу (M21-M25) через реакції різноманітних альдегідів з кетонами для отримання халконів з подальшою реакцією останніх з гідразином і фенілгідразином. Синтезовані сполуки були ідентифіковані за допомогою FT-IR спектроскопії, 1H ЯМР і 13C ЯМР спектроскопії. Біологічна активність синтезованих сполук була попередньо оцінена щодо певних типів грампозитивних (Staphylococcus aureus) і грамнегативних (Escherichia coli) бактерій. Результати показали високий антибактеріальний ефект проти обох типів бактерій за високих концентрацій.
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