Hydrogels Penetration and Sorption Properties in the Substances Release Controlled Processes

Authors: 
Volodymyr Skorokhoda, Nataliya Semenyuk, Joury Melnyk and Oleg Suberlyak

The crosslinked copolymers of 2-hydroxyethylmethacrylate with polyvinylpyrrolidone as granules and membranes have been synthesized and their penetration and sorption-desorption properties have been investigated. The model of mass-transfer from the solid soluble surface through the hydrogel shell has been suggested. The developed materials are able to create encapsulated and granular polymer forms of drugs prolonged release.

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