Тhe influence of thiosulfic acid derivatives on the morphological properties of loach embryos at the initial stages of development

By means of morphological studies, it was established that the influence of thiosulfonate solutions of different structure doesn’t show an inhibition of blastomere division and germ layer formation of the freshwater bony fish, namely weatherfish (MisgurnusfossіlisL). However, under the effect of potassium nitrobenzenethiosulfonate (NTK), at the pre-hatching stage (36thdevelopment stage), that is responsible for the establishment of erythrocyte circulation, external gills predevelopment and the appearance of pigmentation, we observed a delay for approximately 13-16 hours with the imminent vascular pathology. The pronounced changes of cardio-vascular system, which manifested itself in vasodilation, were spotted later on after the NTK influence.The results showed evidence of thiosulfate acid’s derivatives, namely NTK, being promising, highly efficient, non-toxic antithrombotic and antiplatelet remedies. 

тіосульфонати
blastomeres
loach embryos ofMisgurnus fossіlis L.
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