HYDROGELS BASED ON NATURAL POLYMERS STRUCTURED WITH PROPYLENE GLYCOL DIEPOXIDE FOR DRUG DELIVERY

The article presents the conditions of synthesis and the results of characterization of the obtained gelatin and gelatin-alginate hydrogels structured with polypropylene glycol diepoxide. The swelling in water, saline, and model exudate was studied, and the gel fraction and tensile strength of the synthesized samples were determined. The regularities of saturation with drugs and their release into model environments were obtained. The potential use of these materials for transdermal drug delivery is considered.

структурування
gelatin
натрій альгінат
swelling in model media
drug release
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