Amaranth is a multi-purpose crop, known for its wound-healing properties. Amaranth leaves and seeds contain polyphenols and flavonoids that improve wound healing. Ethanol extracts of amaranth seeds of "Lera" and "Ultra" varieties and ethanol extract of leafs Amaranthus retroflexus were obtained. Determination of the content of polyphenolic compounds in the extracts was conducted by the spectrophotometric method with the Folin-Checolteau reagent. The number of flavonoids in the extracts was determined by the spectrophotometric method using aluminum chloride.. The most polyphenolic compounds and flavonoids were found in the extract of leafs Amaranthus retroflexus. More polyphenols and flavonoids were found in the amaranth seed extract of the "Lera" variety than in the extract of the "Ultra" variety.
1. Zupanets, I. A., Bezugla, N. P., Otrishko, I. A., & Ursol, H. M. (2023). Phytotherapy: medicinal products vs BAD. Ukrainian medical journal, 4(156), 1-7. DOI: 10.32471/umj.1680-3051.156.245981
2. Державний експертний центр МОЗ України. (n.d.). Державний реєстр лікарських засобів України. Міністерство охорони здоров’я України. Ресурс: http://www.drlz.com.ua/
3. Cedillo-Cortezano, M., Martinez-Cuevas, L. R., López, J. A. M., Barrera López, I. L., Escutia-Perez, S., & Petricevich, V. L. (2024). Use of Medicinal Plants in the Process of Wound Healing: A Literature Review. Pharmaceuticals, 17(3), 303. https://doi.org/10.3390/ph17030303
4. Shostak, T. A., Kalyniuk, T. G., & Gudz, N. I. (2014). Peculiarities of pharmaceutical development of herbal preparations (Literature review). Phytotherapy, (4), 77-82. Retrieved from https://www.researchgate.net/publication/312897260_OSOBLIVOSTI_FARMACEVTICNOI_ROZROBKI_ROSLINNIH_PREPARATIV
5. Tirus, M. L., & Lykhochvor, V. V. (2023) Amaranth yield depending on variety and seeding rate under conditions of sufficient moisture. Foothill and mountain agriculture and stockbreeding, 73(1), 88-105. DOI: 10.32636/01308521.2023-(73)-1-6
6. Assad, R., Reshi, Z. A., Jan, S., & Rashid, I. (2017). Biology of Amaranths. The Botanical Review, 83, 382–436. https://doi.org/10.1007/s12229-017-9194-1
7. Baraniak, J., & Kania-Dobrowolska, M. (2022). The Dual Nature of Amaranth-Functional Food and Potential Medicine. Foods (Basel, Switzerland), 11(4), 618. https://doi.org/10.3390/foods11040618
8. Barba de la Rosa, A. P., de León-Rodríguez, A., Laursen, B., & S. Fomsgaard, I. (2019). Influence of the growing conditions on the flavonoids and phenolic acids accumulation in amaranth (Amaranthus hypochondriacus L.) leaves. REVISTA TERRA LATINOAMERICANA, 37(4), 449–457. https://doi.org/10.28940/terra.v37i4.541
9. Noori, M., Talebi M., & Nasiri Z. (2015). Seven Amaranthus L. (Amaranthaceae) Taxa Flavonoid Compounds from Tehran Province, Iran. International Journal of Modern Botany, 5(1), 9-17. doi: 10.5923/j.ijmb.20150501.02.
10. Okoye E.I. (2018). Qualitative and Quantitative Phytochemical Analysis and Antimicrobial Screening of Solvent Extracts of Amaranthus hybridus (Stem and Leaves). Chemistry Research Journal, 3(1), 9-13. Retrieved from https://chemrj.org/download/vol-3-iss-1-2018/chemrj-2018-03-01-09-13.pdf
11. Sahoo, H.B., Sahoo, S.K., Mishra, K., & Sagar, R. (2015). Evaluation of the wound-healing potential of Amaranthus viridis (Linn.) in experimentally induced diabetic rats. International Journal of Nutrition, Pharmacology, Neurological Diseases, 5, 50 - 55. DOI: 10.4103/2231-0738.153792
12. Paswan, S. K., Srivastava, S., & Rao, C. V. (2020). Incision Wound healing, Anti-inflammatory and Analgesic activity of Amaranthus spinosus in Wistar rats. Research Journal of Pharmacy and Technology, 13(5), 2439-2444. DOI: 10.5958/0974-360X.2020.00437.0
13. Fejér, J., Kron, I., Eliašová, A., Gruľová, D., Gajdošová, A., Lancíková, V., & Hricová, A. (2021). New Mutant Amaranth Varieties as a Potential Source of Biologically Active Substances. Antioxidants (Basel, Switzerland), 10(11), 1705. https://doi.org/10.3390/antiox10111705
14. Vronska, L. V. (2018). Development of a spectrophotometric method for the determination of flavonoids in shoots of common blueberry. Pharmaceutical Journal, (4), 49–56. https://doi.org/10.11603/2312-0967.2018.4.9703
15. Kniazieva, K. S., Petrina, R. O., Mylyanych, A. O., & Shved, O. V. (2020). Chapter 4. Extracts of callus biomass of Arnica montana and Calеndula officinаlis as a source of amino acids. Publishing House of Polonia University "Educator", 49-60.
16. Akin-Idowu, P. E. , Ademoyegun, O. T. , Olagunju, Y. O. , Aduloju, A. O. , & Adebo, U. G. (2017). Phytochemical Content and Antioxidant Activity of Five Grain Amaranth Species. American Journal of Food Science and Technology, 5(6), 249-255. DOI:10.12691/ajfst-5-6-5
17. Рalombini, S. V., Claus, T., Maruyama, S. A., Gohara, A. K., Souza, A. H. P., Souza, N. E. de ., Visentainer, J. V., Gomes, S. T. M., & Matsushita, M.. (2013). Evaluation of nutritional compounds in new amaranth and quinoa cultivars. Food Science and Technology, 33(2), 339–344. https://doi.org/10.1590/S0101-20612013005000051