Drug Micro-Carriers Based on Polymers and Their Sterilization

2018;
: pp. 473-487
1
Instituto de Macromoléculas, Centro de Tecnologia, Universidade Federal do Rio de Janeiro
2
Instituto de Macromoléculas, Centro de Tecnologia, Universidade Federal do Rio de Janeiro
3
Instituto de Química, Universidade de Brasilia
4
Engenharia Nuclear/COPPE, Centro de Tecnologia, Universidade Federal do Rio de Janeiro
5
1 Instituto de Macromoléculas, Centro de Tecnologia, Universidade Federal do Rio de Janeiro 2 Engenharia Civil/COPPE, Centro de Tecnologia, Universidade Federal do Rio de Janeiro

This paper presents the main aspects regarding the production of biodegradable microspheres, the optimization of parameters in the drug encapsulation process, the techniques available for polymeric systems sterilization and the effects of γ-irradiation on microparticles.

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