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  2. All Volumes and Issues
  3. Volume 16, Number 1, 2022
  4. Synthesis and Properties of Phosphorus-Containing Pseudo-Poly(Amino Acid)sof Polyester Type Based on N-Derivatives of Glutaminic Acid

Synthesis and Properties of Phosphorus-Containing Pseudo-Poly(Amino Acid)sof Polyester Type Based on N-Derivatives of Glutaminic Acid

JCCT.
2022;
Volume 16, Number 1
: pp. 51–58
https://doi.org/10.23939/chcht16.01.051
Authors:
  1. Anna Stasiuk
  2. Nataliia Fihurka
  3. Vasyl Vlizlo
  4. Sofiia Prychak
  5. Dmytro Ostapiv
  6. Serhii Varvarenko
  7. Volodymyr Samaryk
1
Lviv Polytechnic National University
2
Uppsala University, Division of Nanotechnology and Functional Materials
3
Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies
4
Lviv Polytechnic National University
5
Institute of animal biology of NAAS
6
Lviv Polytechnic National University
7
Lviv Polytechnic National University

Poly(phosphoeter)s (PPE)s are a class of polymers possessing a high chemical functionality and biodegradability. Novel, glutamic acid based poly(phosphoeter)s were synthesized by the Steglich reaction. The developed synthetic approach allows controlling the composition and the structure of PPEs, and therefore their physical and colloidal properties. The studies on solubilization and cytotoxicity in vitro proved the potential of PPEs for drug delivery applications.

poly(phosphoester)s
pseudo-poly(amino acid)s
glutamic acid
polyethylene glycol
Steglich reaction
drug delivery
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