1. JCCT
  2. Всі випуски
  3. Випуск 17, Номер 3, 2023
  4. Синтез та антимікробна активність комплексу саліцилальдегідна основа шиффа cu(ii) та його каталітична активність у реакціях n-арилювання

Синтез та антимікробна активність комплексу саліцилальдегідна основа шиффа cu(ii) та його каталітична активність у реакціях n-арилювання

JCCT.
2023;
Випуск 17, Номер 3
: cc. 557 - 566
https://doi.org/10.23939/chcht17.03.557
Автори:
  1. Afrooz Majdi-Nasab
  2. Fariba Heidarizadeh
  3. Hossein Motamedi
1
Shahid Chamran University of Ahvaz
2
Shahid Chamran University of Ahvaz
3
Shahid Chamran University of Ahvaz

Синтезовано комплекс саліцилальдегідна основа Шиффа-Cu (1:1 [M:L] хелат) з використанням саліцилальдегіду, сечовини та CuCl2. Проведено оцінювання його каталітичної активності для реакції N-арилювання ароматичних амінів (1H-індол, 1H-піразол, 1H-імідазол, 1H-бензо [d][1,2,3]триазол та анілін) арилгалогенідами. Реакція не по-требує арилборних кислот як активного джерела арилу або каталізатора на основі паладію. Мідь є дешевшою, ніж багато інших каталізаторів, а необхідні ліганди зазвичай мають досить просту структуру і коштують недорого. Показано, що при правильному виборі ліганду є можливість змінювати розчинність, реакційну здатність та ефективність реакції. Структура та склад нового комплексу підтверджені методами FT-IR, UV-Vis, атомно-абсорбційної спектроскопії, елементарного аналізу та TGA/DTA. Встановлено, що комплекс Cu має значну антибактеріальну активність щодо стандартних видів Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus і Bacillus subtilis.

комплекс саліцилальдегідна основа Шиффа-Cu
антимікробне дослідження
каталітична активність
N-арилювання
арилгалогенід
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