Film hydrogels on the basis of polyvinylpyrrolidone copolymers with regulated sorption-desorption characteristics

Authors: 

Volodymyr Skorokhoda, Yuriy Melnyk, Natalia Semenyuk, Oleh Suberlyak

Volodymyr Skorokhoda-1. Yuriy Melnyk-1, Natalia Semenyuk-1, Oleh Suberlyak-1

  1. Lviv Polytechnic National University, 12, S. Bandera St., 79013 Lviv, Ukraine vskorokhoda@yahoo.com

The hydrogel film composites of biomedical purpose based on copolymers of polyvinylpyrrolidone with 2-hydroxyethylmethacrylate have been synthesized. The influence of filler nature, quantity and composition on the regularities of obtaining, structure and properties of hydrogels have been determined. Synthesized hydrogel composites are recommended to be used for the controlled drug release systems.

[1] Skorokhoda V., Semenyuk N., Kostiv U. et al.: Chem. Chem. Technol., 2013, 7, 95. 
[2] Skorokhoda V., Semenyuk N., Melnyk Y. et al.: Chem. Chem. Technol., 2009, 3, 117. 
[3] Melnyk Y., Halyshyn O. and Skorokhoda V.: Khim. Prom. Ukrainy, 2009, 4, 26. 
[4] Melnyk Y., Semenyuk N., Yatsulchak G. et al.: Composite Polymer Hydrogels with Prolonged Drug Release [in:] Novikov V. (Ed.), Modern Directions in Chemistry, Biology, Pharmacy and Biotechnology. Lviv Polytechnic PH, Lviv 2015, 179.
[5] Menson J., Sperlinh L. Polimiernyye Smiesi i Kompozity. Khimiya, Moskva 1979. 
[6] Skorokhoda V., Semenyuk N., Lukan G. et al.: Polym. J., 2006, 2, 155. 
[7] Semenyuk N.: Khim. Prom. Ukrainy, 2008, 1, 35. 
[8] Suberlyak O., Semenyuk N., Dudok G. et al.: Rus. J. Appl. Chem., 2012, 85, 830. https://doi.org/10.1134/S1070427212050254
[9] Suberlyak O., Skorokhoda V. and Semenyuk N.: Eng. Biomater., 2007, 63-64, 14. 
[10] Suberlyak O., Melnyk Y. and Skorokhoda V.: Mater. Sci., 2015, 50, 889. https://doi.org/10.1007/s11003-015-9798-8
[11] Turkevych M.: Farmacevtychna Khimiya. Vyshcha shkola, Kyiv 1973.